Article Sphere Logo
"Lung Mesothelioma Asbestos" Article
 Article Directory Home All Categories Disease And Conditions Lung Mesothelioma Asbestos

Asbestos and Malignant Mesthelioma

By Expert Author: Jim Kreinbrink | View Article Summary
Word Count: 494 words | Views: 606 view(s)
Jim Kreinbrink

Many people are wondering about the risks of asbestos exposure and getting malignant mesothelioma. Mesothelioma is a type of cancer on the pleura, or lining of the lungs. It can lead fluid in the lungs, difficulty breathing, and eventually death. When it comes to how our bodies age and handle illness, 65% depends on the environment, like the things we feed, expose, and do to our bodies. The remaining 35% is due to genetics, that wonderful nuclear and mitochondrial DNA that we got from ours parents and mothers, respectively.

When we think about environment, consider the following study. A 35-year period evaluation of workers in an asbestos factory in Poland revealed that increased rates of lung cancers, pleural mesothelioma, and all malignant cancers were higher in these workers than in the general population. Of the 4,187 subjects studied (2805 men and 1382 women), five died from pleural mesothelioma. Also, the risk for these types of illness did not differ between those that had a preceeding documented diagnosis of lung asbestosis and those that did not. So, where people work, and the polutants they are exposed to, clearly influence disease risks.

Now with genomics laboratories, investigation of disease risk is taken to a new level. A recent study in Northwest Italy evaluated single nucleotide DNA polymorphisms in 4 genes responsible for DNA repair. Polymorphisms are like typos in the DNA language. The assumption was that sloppy DNA repair increased the risk for this cancer when a gene-damaging substance like asbestos was thrown into the picture. Itâ€s like trying to fix an important system with an entire chapter ripped out of the repair manual. So seven different variations of these 4 genes were studied in 81 malignant mesothelioma patients and 110 of their age-matched and sex-matched controls. All subjects were residents of Casale Monferrato, a town polluted with asbestos. The results showed that with one type of polymorphism (or DNA typo) a 2.147 oddds ratio existed for this disease, another variant (or DNA typo) had a 4.09 odds risk ratio. These genetic variations can certainly put people at an increased risk of developing the cancer. This is valuable information because the residents of this town can now look at their family genetics and give more consideration about whether or not they should move out of there!

Environment and genetics…we are getting more options now than ever before to learn about our risks of getting cancers, like malignant mesothelioma. If you have any concerns about a history of personal asbestos exposure, I encourage you to explore with your physician or health care provider what diagnostic tools are available for further evaluation.

References:
Dianzani I, et al. Polymorphisms in DNA repair genes as risk factors for asbestos-related malignat mesothelioma in a general population study. Mutant Res. 2006 Marc 23; (epub ahead of print)
Wilezynska U, Szymezak W, Szeszenia-Dabrowska N. Mortality from malignant neoplasms among workers of an asbestos processing plant in Poland: results of prolonged observation. Int J Occup Med Environ Health 2005; 18(4):313-26.
About the Author/Author Bio

Natalie Kather, MD, is a diplomate of the American Board of Anti-Aging Medicine and diplomate of the Amercian Board of Family Medicine. She specializes in using the latest longevity and anti-aging research to extend and improve her clients' lives.

Article Source: http://www.articlesphere.com/Article/Asbestos-and-Malignant-Mesthelioma/47582

Article Tags: disease and illness, lung mesothelioma asbestos, mesothelioma, lung cancer, breathing difficulty, asbestos, asbesthos exposure

Article Submitted: 2006-08-27 | This Article has been viewed 606 times.

Comments on this Article


More "Lung Mesothelioma Asbestos" Related Articles

 
 

Listed below are more articles related to the above article from the "Lung Mesothelioma Asbestos" article category.

People interested in the above article "Asbestos and Malignant Mesthelioma" are also interested in the related articles listed below:

 
Among the various type of cancer deaths, lung cancer is responsible for 29 percent of that. Hence, you can begin protecting yourself now by arming yourself with the general facts on lung cancer before it's too late.
Early detection of lung cancer warning signs - or any other types of illnesses - is crucial in helping to find a cure for the disease. Indeed, the earlier one is able to find out about the disease, the better chances they have for combating the illness.
The effects of lung cancer on the patient's body can differ according to the type and stage of the disease. However, studies are now focused towards the unpleasant impact of treatments intended to cure the disease in patients. Although these have been recognized as temporary effects only, it still does produce enough good to the health of the patients.
A pneumothorax is also known as a collapsed lung. It is basically the accumulation of air inside the pleural cavity. A pneumothorax if left untreated can be deadly. Below are some of the symptoms and treatments available. The main symptom of a collapsed lung is shortness of breath and chest pain. These symptoms however could be the result of a multitude of other problems so if you experience these symptoms you should get yourself to a doctor or hospital immediately.
No parent will get a good night sleep when his baby is persistently coughing and breathing for him is difficult. You think that it is no ordinary cold or cough. It is something else. You may want to check if your baby is suffering from Bronchiolitis.
Ever heard your doctor mention the term bronchitis? This is actually a chronic or acute swelling or soreness of the mucous membranes of the respiratory system's tracheobronchial tree (trachea or windpipe and the bronchial tubes). Under some circumstances, it may or may not be contagious.
Every year, you may suffer from a disease that can render you sick and disabled. Diseases that you cross paths with can immobilize you and can stop you from going to work to earn money, or will not allow you to go to school and catch up with the latest lessons. You have to consider that in order to get back to work or to school as soon as possible, you have to cure the disease in order to become a productive member of society again.
 
Article Directory Home All Categories Disease And Conditions Lung Mesothelioma Asbestos
 

Can't find what you're looking for? Try Google Search!
 
 
(We serve worldwide - Locations updated as at Sunday, 05 July 2009 03:13 am , Singapore)
United States of America, USA . United Kingdom, UK (England, Scotland, Wales, Northern Ireland) . Canada . Afghanistan . Albania . Algeria . American Samoa . Andorra . Angola . Anguilla . Antarctica . Antigua & Barbuda . Argentina . Armenia . Aruba . Australia . Austria . Azerbaijan . Bahamas . Bahrain . Bangladesh . Barbados . Belarus . Belgium . Belize . Benin . Bermuda . Bhutan . Bolivia . Bonaire . Bosnia-Herzegovina . Botswana . Brazil . British Virgin Islands . Brunei Darrusalam . Bulgaria . Burkina Faso . Burundi . Cambodia . Cameroon . Cape Verde . Cayman Islands . Central African Republic . Chad . Channel Islands . Chile . China . Christmas Island . Colombia . Comoros . Congo . Congo (Dem. Rep.) . Cook Islands . Costa Rica . Cote d'Ivoire . Croatia . Cuba . Curacao . Cyprus . Czech Republic . Denmark . Djibouti . Dominica . Dominican Republic . East Timor . Ecuador . Egypt . El Salvador . Equatorial Guinea . Eritrea . Estonia . Ethiopia . Falkland Islands and Dependencies . Faroe Islands . Fiji . Finland . France . French Guiana . French Polynesia . Gabon . Gambia . Gaza . Georgia . Germany . Ghana . Gibraltar . Greece . Greenland . Grenada . Guadeloupe . Guam . Guatemala . Guinea . Guinea-Bissau . Guyana . Haiti . Hawaiian Islands . Honduras . Hong Kong . Hungary . Iceland . India . Indonesia . Iran . Iraq . Isle Of Man . Israel . Italy . Ivory Coast . Jamaica . Japan . Johnston Atoll . Jordan . Kazakhstan . Kenya . Kiribati . Korea (North) . Korea (South) . Kuwait . Kyrgyzstan . Laos . Latvia . Lebanon . Leeward Islands . Lesotho . Liberia . Libya . Liechtenstein . Lithuania . Luxembourg . Macau . Macedonia . Madagascar . Malawi . Malaysia . Maldives . Mali . Malta . Marshall Islands . Martinique . Mauritania . Mauritius . Mexico . Micronesia (Federated States) . Midway Islands . Moldova . Monaco . Mongolia . Montserrat . Morocco . Mosquito Coast . Mozambique . Myanmar (Burma) . Namibia . Nauru . Navassa Island . Nepal . Netherlands . Netherlands Antilles . New Caledonia . New Zealand . Nicaragua . Niger . Nigeria . Niue . Norfolk Island . Northern Mariana Islands . Norway . Oman . Pakistan . Palau . Palestine . Panama . Papua New Guinea . Paracel Islands . Paraguay . Peru . Philippines . Pitcairn Islands . Poland . Portugal . Puerto Rico . Qatar . Reunion . Romania . Russia . Rwanda . Ryukyu Islands . Saint Helena . Saint Kitts and Nevis . Saint Lucia . Saint Pierre & Miquelon . Saint Vincent & The Grenadines . Samoa . San Marino . Sao Tome & Principe . Saudi Arabia . Senegal . Serbia . Seychelles . Sierra Leone . Singapore . Slovakia . Slovenia . Solomon Islands . Somalia . South Africa . Spain . Sri Lanka . Sudan . Suriname . Swaziland . Sweden . Switzerland . Syria . Taiwan . Tajikistan . Tanzania . Thailand . Togo . Tonga . Transkei . Trinidad & Tobago . Tunisia . Turkey . Turkmenistan . Turks and Caicos Islands . Tuvalu . US Virgin Islands . Uganda . Ukraine . United Arab Emirates . Upper Volta . Uruguay . Uzbekistan . Vanuatu . Vatican City (Holy See) . Venezuela . Vietnam . Wake Island . Windward Islands . Yemen . Yugoslavia . Zaire . Zambia . Zimbabwe
Copyright © 2005 - by Larry Lim, Singapore - Article Search Engine Directory at ArticleSphere.com™
All Rights Reserved Worldwide. All Trademarks and Servicemarks are the property of the respective owners.
French Spanish Bulgarian Chinese (Simplified) Chinese (Traditional) Croation Czech Danish Dutch Finnish German Greek Italian Japanese Korean Norwegian Polish Portuguese Romanian Russian Serbian Slovak Swedish Arabic Hebrew Hungarian Thai Turkish English US