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Stem Cell Therapy Stamcellebehandling By Expert Author: Madalyn Ward, DVM Ved ekspert Forfatter: Madalyn Ward, DVM
View Summary \| Submitted: 2008-04-23 \| Word Count: 876 words \| Views: 303 view(s) Vis Resumé \| Forelagt: 2008-04-23 \| Ordoptælling: 876 ord \| Views: 303 se (s)

Stem cells and stem cell therapy have received a lot of news coverage lately, some of it controversial, so this month I've decided to discuss stem cells in general, along with several approaches to stem cell therapy. Stamceller og stamceller terapi har fået en masse nyheder dækning seneste, noget af det kontroversielle, så denne måned har jeg besluttet at diskutere stamceller generelt, sammen med flere tilgange til stamcellebehandling. The stem cell therapies I advocate are both legal and simple, especially with the advent of a new nutritional product called Stemplex, which I'll discuss a little later. Den stamcellebehandling Jeg går ind for, er både juridisk og enkel, især med indførelsen af en ny ernæringsmæssige produkt kaldet Stemplex, som jeg vil diskutere lidt senere. But first, a little about the stem cell itself...

Embryonic Versus Adult Stem Cells Embryonale versus voksne stamceller
A stem cell is an undifferentiated cell that can renew itself and develop into at least three different types of tissue. En stamcelle er en udifferentieret celle, der kan forny sig og udvikle sig til mindst tre forskellige typer af væv. Embryonic stem cells are derived from early stage embryos and have the ability to differentiate into all adult cell types. Embryonale stamceller er afledt fra tidligt stadium embryoner og har evnen til at differentiere til alle voksne celletyper. Embryonic stem cells behave in a consistent way under a microscope but are much less predictable when injected into the body. Embryonale stamceller opfører sig på en meningsfuld måde under et mikroskop, men er langt mindre forudsigelig, når der sprøjtes ind i kroppen. They can offer some benefits for research but their use is controversial and they are not useful for actual treatments. De kan tilbyde nogle fordele for forskning, men deres anvendelse er kontroversiel, og de er ikke nyttigt for faktiske behandlinger.

Adult stem cells reside in post-fetal animals. Voksne stamceller opholde sig i post-føtal dyr. Examples are linage-committed such as hematopoietic stem cells that become red or white blood cells, or mesenchymal stem cells that can become many types of tissue, including bone, tendon, ligament, cartilage, heart, liver, or nerves. Eksempler herpå er linage-begået såsom bloddannende stamceller, der bliver røde eller hvide blodlegemer, eller mesenchymale stamceller, der kan blive mange typer væv, herunder ben, afskæres, ligament, brusk, hjerte, lever, eller nerverne. Sources of adult stem cells include bone marrow, fat, brain tissue, and muscles. Kilder af voksne stamceller omfatter knoglemarv, fedt, hjernevæv, og muskler. Of all the tissues, fat yields the largest numbers of mesenchymal stem cells, while bone marrow or umbilical blood yield more stem cells that will become red or white blood cells. Af alle de væv, fedt giver det største antal mesenchymale stamceller, mens knoglemarv og umbilical blod udbyttet mere stamceller, der bliver røde eller hvide blodlegemer.

Types of Stem Cells Typer af stamceller
There are several different categories of stem cells, including autologous, allogenic, and xenogenic. Der er flere forskellige kategorier af stamceller, herunder autolog, allogene, og xenogen. Autologous stem cells are those derived from the same animal. Autologe stamceller, er dem, der stammer fra de samme dyr. These are best for transplanting since there is no concern about them being rejected. Disse er bedst til omplantning, da der ikke er nogen bekymring for dem at blive afvist. Allogenic stem cells are from a donor of the same species. Allogene stamceller fra en donor af samme art. Since stem cells do not have the standard cell surface markers that would trigger immune response, these cells can potentially be used without fear of rejection by the host tissue. Da stamceller ikke har den standard celleoverfladereceptorer markører, der ville udløse immunrespons, disse celler kan potentielt anvendes uden frygt for afvisning af værten væv. Xenogenic stem cells come from a donor of another species, such as a pig. Xenogen stamceller kommer fra en donor af en anden art, sådan som et svin. Although one would expect these cells to be rejected, because of their unique characteristics they can survive, in some cases, when injected into the body of another species. Selv om man kunne forvente disse celler til at blive afvist på grund af deres særlige kendetegn, de kan overleve i nogle tilfælde, når det sprøjtes ind i kroppen af en anden art.

How Do Stem Cells Work? Hvordan kan stamceller arbejde?
The most commonly cited function of stem cells is their ability to differentiate into different tissues but they also have other abilities that can be very beneficial for healing. De hyppigst citerede funktion af stamceller er deres evne til at differentiere i forskellige væv, men de har også andre evner, som kan være meget gavnlig for helbredelse. Stem cells produce over 30 types of growth factors and tissue chemicals that stimulate healing. Stamceller producerer over 30 typer af vækst faktorer og væv kemikalier, som stimulerer helbredelse. Stem cells help recruit other local and systemic stem cells to focus on repairing damaged tissue. Stamceller hjælpe rekruttere andre lokale og systemiske stamceller til at fokusere på at reparere beskadiget væv. They are also active in immune modulation to promote or suppress T-cell function. De er også aktive i immune modulation til at fremme eller undertrykke T-celle funktion.

Stem cells are triggered to move into an area by signals from the tissue based on chemical, neural, and mechanical changes. Stamceller er udløst for at flytte til et område af signaler fra væv baseret på kemiske, neurale, og mekaniske ændringer. Hypoxia, which is lack of oxygen, and inflammation are strong triggers for stem cells to target an injury, although the stems cells account for less than half of the new tissue formed. Hypoksi, der er mangel på ilt, og inflammation er stærke faktorer, der udløser stamceller til at target en skade, selv om de stammer celler tegner sig for mindre end halvdelen af de nye væv dannes. The rest of the repair is done by other cells recruited and managed by the initial stem cells. Resten af reparation er udført af andre celler rekrutteres og forvaltes af den oprindelige stamceller. This is why very tiny injections of stem cells are used. Dette er grunden til meget små injektioner af stamceller bruges. Injecting larger numbers of stem cells into an injured area can actually interfere with healing, since some of the injected cells die and must be removed during the healing process. Injektion af et større antal af stamceller i en såret område rent faktisk kan blande sig med healing, da nogle af de injicerede celler dør og skal fjernes i løbet af den helbredende proces.

Under ideal conditions stem cells would respond to injuries and healing would occur. Under ideelle betingelser stamceller ville reagere på skader og helbredelse ville opstå. Factors that affect stem cell response include the age of the animal, the fitness of the animal, and the level of free radicals in the body. Faktorer, der påvirker stamceller svar indeholde dyrets alder, egnethed af dyret, og det niveau af frie radikaler i kroppen. Free radicals damage all cells, including stem cells. Frie radikaler skader alle celler, herunder stamceller.

Stem Cell Therapy in Horses Stamcellebehandling i heste
In horses the repair of ligament injuries has shown the most promise. Hos heste reparation af personskader ligament har vist de mest lovende. Injuries to the ligaments in a horse's lower leg are notoriously difficult to heal. Personskader til ledbånd i en hestens ben er notorisk vanskelige at helbrede. Stem cells harvested from the injured horse's own fat can be injected directly into the area of ligament damage to stimulate healing with less scarring, which decreases the chance of re-injury. Stamceller høstet fra såret hest eget fedt kan injiceres direkte i det område af ligament skade at stimulere helbredelse med mindre ar, som nedsætter chance for at re-skade. In some cases bone marrow is harvested, but this tissue must be cultured to increase the numbers of mesenchymal stem cells. I nogle tilfælde knoglemarv er høstet, men dette væv skal dyrkes for at øge mængden af mesenchymale stamceller.

Another promising stem cell therapy is based on increasing the numbers and activity of the animal's own stem cells using nutrition. Et andet lovende stamceller terapi er baseret på at øge antallet og aktiviteten af dyrets egne stamceller ved hjælp af ernæring. Just as scientists discovered that beta glucan is a nutrient that stimulates the white blood cells called macrophages, researchers have now identified nutrients that stimulate and cause the proliferation of stem cells. Ligesom videnskabsmænd opdaget, at beta-glucan er et næringsstof, som stimulerer de hvide blodlegemer kaldet makrofager, forskere har nu identificeret næringsstoffer, der stimulerer og forårsage spredning af stamceller. Based on this research, Simplexity Health has developed a product called Stemplex (TM) that contains green tea extract, wild blueberry, the amino acid carnosine, blueberry extract, vitamin D, and blue-green algae. Baseret på denne forskning, Simplexity Sundhed har udviklet et produkt kaldet Stemplex (TM), der indeholder grøn te-ekstrakt, vilde blåbær, den aminosyre carnosine, blåbær ekstrakt, vitamin D, og blå-grønne alger. I have been using this product on my own horse, who has chronically contracted and sore heels. Jeg har brugt denne vare på min egen hest, der har kronisk kontraheret og ømme hæle. Within just a month I am seeing improvement in his gait. Inden for bare en måned jeg se en forbedring i sin gang.

Stem cell therapy has huge potential and should be considered as a healing treatment for injuries or organ damage. Stamcelle-terapi er enormt potentiale og bør betragtes som en helbredende behandling for skader eller organ skader. In addition, systemic stem cell therapy shows promise in treating neurological conditions. Hertil kommer, systemisk stamcellebehandling viser løfte i behandling af neurologiske betingelser. Providing nutritional support for the body's own stem cells is always a good option, which can be supplemented by using targeted injections of harvested stem cells. Forudsat ernæringsmæssig støtte til kroppens egne stamceller er altid en god mulighed, som kan suppleres ved hjælp af målrettede injektioner af høstede stamceller. These injections are especially useful when nutritional support does not create enough healing effect or the injured area, such as ligaments in a horse's lower leg, has poor circulation. Disse indsprøjtninger er især nyttig, når ernæringsmæssig støtte ikke skaber nok helbredende virkning eller tilskadekomne område, såsom ledbånd i en hestens ben, har dårlig omsætning.

About the Author/Author Bio Om Forfatter / Author Bio

Madalyn Ward, DVM, owns Bear Creek Veterinary Clinic in Austin, Texas. Madalyn Ward, DVM, ejer Bear Creek Veterinary Clinic i Austin, Texas. She is certified in Veterinary Homeopathy and Equine Osteopathy. Hun er certificeret i Veterinær homøopati og Equine Muskelterapi. Memberships include American Veterinary Medical Association, American Association of Equine Practitioners, American Holistic Veterinary Medical Association, Texas Veterinay Medical Association and the Academy of Veterinary Homeopathy. Medlemskaber omfatter American Veterinary Medical Association, American Association of Equine praktiserende læger, American holistisk Veterinary Medical Association, Texas veterinærområdet Medical Association og Academy of Veterinary homøopati. She has authored several books and publishes the monthly newsletter, "Holistic Horsekeeping." Hun er forfatter til flere bøger og offentliggør det månedlige nyhedsbrev, "Holistisk Horsekeeping."

Contact Kontakt
Madalyn Ward DVM Madalyn Ward DVM
11608 FM 1826 11.608 FM 1826
Austin, TX 78737 Austin, TX 78737
303-575-1170 303-575-1170
www.holistichorsekeeping.com www.holistichorsekeeping.com
www.horseharmony.com www.horseharmony.com
www.yourhorsebook.com www.yourhorsebook.com

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