Artikel Sphere-logoet
Main Article Categories Main artikel kategorier

Alternative Medicine Alternativ medicin
Arts And Entertainment Kunst og underholdning
Automotives Automotives
Beauty Skønhed
Business Forretning
Communications Kommunikation
Computer And Technology Computer og teknologi
Disease And Illness Sygdom og sygdom
Finance Finans
Food And Beverage Fødevarer og drikkevarer
Health And Fitness Sundhed og fitness
Home And Family Hjem og familie
Home Based Business Home baseret Business
Insurance Forsikring
Internet And E-Business Internet og e-business
Legal Juridisk
News And Society Nyheder og samfund
Pets And Animals Kæledyr og dyr
Product Reviews Produkt Anmeldelser
Real Estate Real Estate
Recreation And Sports Sport og fritid
Reference And Education Reference-og Uddannelsesudvalget
Self Improvement Self Forbedring
Shopping Shopping
Travel And Leisure Rejser og fritid
Women Health And Fitness Kvinders sundhed og fitness
Women Interests And Issues Kvinders interesser og spørgsmål
Work At Home Arbejde i hjemmet
Writing And Speaking Skrivning og taler
All 511 Categories Alle 511 Kategorier
"Alternative Medicine" Article "Alternativ medicin" artikel
Article Directory Home Artikel Directory Home Alternative Medicine Alternativ medicin

TLR10 - Cluster of Differentiation 290 TLR10 - Cluster af Differentiering 290

By Expert Author: Stephen Jones Ved ekspert Forfatter: Stephen Jones
View Summary | Submitted: 2008-07-11 | Word Count: 370 words | Views: 86 view(s) Vis Resumé | Forelagt: 2008-07-11 | Ordoptælling: 370 ord | Views: 86 se (s)
Stephen Jones
Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. Toll-lignende receptor 10 (TLR10) ofte kendt som CD290 (klynge af differentiering 290), er den mest nylig identificeret human homolog af Drosophila TOLL protein. Human TLR10 is an orphan member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern. Human TLR10 er et sjældent medlem af Toll-lignende receptor familie, der genkender patogen-tilknyttede molekylære mønster. Like other members of the TLR family, TLR10 contains a signal peptide, multiple leucine-rich repeats, a cysteine-rich domain, a transmembrane domain, and a cytoplasmic TOLL interleukin-1 receptor domain. Ligesom andre medlemmer af TLR familie, TLR10 indeholder et signal peptid, flere leucin-rige gentager, en cystein-rige domæne, en transmembrane domæne, og en cytoplasmic TOLL interleukin-1 receptor domæne. The human TLR10 gene occupies 3,269 bases arranged in three exons on the short arm of chromosome 4 (4p14) and encodes an 811-amino acid protein, approximately 50% identical to TLR1 and to TLR6. Den menneskelige TLR10 gen indtager 3269 baser indrettet i tre exons på den korte arm af kromosom 4 (4p14) og koder en 811-amino acid protein, at cirka 50% identisk med TLR1 og TLR6. TLR10 is most closely related to TLR1 and TLR6 with 48% and 46% overall amino acid identity, respectively. TLR10 er meget tæt forbundet med TLR1 og TLR6 med 48% og 46% i alt aminosyre identitet, hhv. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene (1). Multiple alternativt splejset afskrift varianter kodning samme protein er blevet fundet for dette gen (1).

In vivo, TLR10 mRNA expression is highest in immune system-related tissues including spleen, lymph node, thymus, tonsil. In vivo, TLR10 mRNA udtryk er højest i immunsystemet-relateret væv, herunder milt, lymfeknude, brisler, tonsiller. TLR10 mRNA is most highly expressed on B cells. TLR10 mRNA er mest udtrykt på B-celler. In vitro, TLR10 is moderately upregulated by autocrine IFN-γ, IL-1β, IL-6, IL-10, and TNF-α in PMA-differentiated THP-1 cells. In vitro, TLR10 er moderat upregulated ved autocrine IFN-γ, IL-1β, IL-6, IL-10, og TNF-α i PMA-opdelte THP-1 celler. TLR10 mRNA expression in THP-1 cells is elevated after exposure to both Gram-positive and Gram-negative bacteria. TLR10 mRNA udtryk i THP-1 celler er forhøjet efter udsættelse for både Gram-positive og Gram-negative bakterier. Ex vivo, monocyte TLR10 expression increases while granulocyte expression decreases on exposure to Gram-negative bacteria. Ex vivo, monocyt TLR10 udtryk stigninger, mens granulocyt udtryk falder for eksponering for Gram-negative bakterier. (2, 3) (2, 3)

Due to absent of its rat homologue, the natural ligand for TLR10 has not been identified yet. På grund af fravær af sin rotte homologué, den naturlige ligand for TLR10 er endnu ikke blevet identificeret. Genomic studies indicate that TLR10 is in the same locus that contains TLR1 and TLR6 and are also structurally similar to each other. Genom-undersøgelser viser, at TLR10 er i samme locus, der indeholder TLR1 og TLR6 og er også strukturelt ligner hinanden. It has been speculated that, like TLR1 and TLR6, TLR10 may form a heterodimer with TLR2 and thereby be sensitive to similar pathogen-associated molecular patterns (PAMPs). Det har været spekulationer fremme om, at ligesom TLR1 og TLR6, TLR10 kan danne en heterodimer med TLR2 og dermed er følsomt over for lignende patogen-tilknyttede molekylære mønstre (PAMPs). Recent studies have shown that TLR10 was not only able to homodimerize but also heterodimerize with TLRs 1 and 2. Nylige undersøgelser har vist, at TLR10 ikke kun var i stand til at homodimerize men også heterodimerize med TLRs 1 og 2. (1)

TLR10 has been identified as a potential asthma candidate gene because early life innate immune responses to ubiquitous inhaled allergens and PAMPs may influence asthma susceptibility and thus TLR10 genetic variation may often contributes to asthma risk. TLR10 er blevet identificeret som en potentiel kandidat astma-genet, fordi tidlige liv medfødte immunrespons til allestedsnærværende inhalerede allergener og PAMPs kan påvirke astma følsomhed og dermed TLR10 genetiske variation kan ofte bidrager til astma risiko. (4)

References: Referencer:
1. The Journal of Immunology, 2005, 174: 2942-2950. Journal of Immunology, 2005, 174: 2942-2950.
2. Chuang, T. and RJ Ulevitch (2001) Biochim. Chuang, T. og RJ Ulevitch (2001) Biochim. Biophys. Acta 1518:157. Acta 1518:157.
3. Zarember, KA and PJ Godowski (2002) J. Immunol. Zarember, KA og PJ Godowski (2002) J. Immunol. 168:554.
4. Hornung, V. et al. Hornung, V. et al. (2002) J. Immunol. (2002) J. Immunol. 168:4531.
About the Author/Author Bio Om Forfatter / Author Bio

IMGENEX India Pvt Ltd. the only biotech company in Orissa and one of its kinds in Eastern India. IMGENEX India Pvt Ltd den eneste biotekvirksomhed i Orissa og en af sin slags i det østlige Indien. IMGENEX India started in Oct as an outsourcing branch of IMGENEX Corporation , San Diego, USA. IMGENEX Indien begyndte i oktober som en outsourcing filial af IMGENEX Corporation, San Diego, USA. Find out more information about Toll-like receptors . Få mere information om Toll-lignende receptorer.

Article Source: http://www.articlesphere.com/Article/TLR10---Cluster-of-Differentiation-290/154445 Artikel Kilde: http://www.articlesphere.com/Article/TLR10---Cluster-of-Differentiation-290/154445

Article Tags: alternative medicine , toll-like receptors Artikel Tags: alternativ medicin, vejafgift-lignende receptorer

This Article has been viewed 86 times. Denne artikel er blevet set 86 gange.

Comments on this Article Henvendelse om denne artikel


More "Alternative Medicine" Related Articles Mere "alternativ medicin" relaterede artikler

Listed below are more articles related to the above article from the "Alternative Medicine" article category. Nedenstående liste omfatter flere artikler relateret til ovenstående artikel fra "Alternativ medicin" Artikel kategori.

People interested in the above article "TLR10 - Cluster of Differentiation 290" are also interested in the related articles listed below: Folk er interesseret i ovenstående artikel "TLR10 - Cluster af Differentiering 290" er også interesseret i de relaterede artikler anført nedenfor:

Reiki can be shared as a family. Reiki kan deles som en familie. When thought of it this way, it would increase for you and makes you whole. Når tænkt på det på denne måde, ville det øge for dig og gør dig hel. Reiki can be shared not just with the rest of the members of your family but to others that are close to your heart. Reiki kan deles ikke bare med resten af medlemmerne af din familie, men for andre, som er tæt på dit hjerte. Oftentimes, Reiki teachers and masters have families that don’t fully understand what Reiki really means and what it can do. Oftentimes, Reiki lærere og skibsførere har familier, som ikke fuldt ud forstår, hvad Reiki betyder reelt, og hvad den kan gøre. But even so, if the members of your family are willing to support each other then eventually, Reiki will be theirs too. Men selv så, hvis medlemmer af din familie er villige til at støtte hinanden, så i sidste ende, Reiki vil være dem også.
Usui Sensei, the recognized founder of Usui Reiki once said, “Just for today, do not worry. Usui Sensei, den anerkendte grundlægger af Usui Reiki engang sagde, "Bare for i dag, skal du ikke bekymre dig. Be filled with gratitude.” There are reasons why the great Reiki teacher uttered such words. Være fyldt med taknemmelighed. "Der er grunde til, at den store Reiki lærer har sagt sådanne ord. And it’s primarily because he knows how much power your thoughts and statements have on you. Og det er først og fremmest fordi han ved, hvor meget strøm dine tanker og udtalelser har om dig.
Warren Buffet once said, "Somebody's sitting in the shade today because someone planted a tree a long time ago." Warren Buffet sagde engang: "Nogen mødet i skyggen i dag, fordi en person har plantet et træ for længe siden." This concept can be applied to becoming wealthy and also to becoming healthy. Dette begreb kan anvendes til at blive rige og også til at blive raske. By choosing to incorporate mindful, healthy lifestyle choices and preventive health care modalities into our lives today, we can enjoy the shade for years to come. Ved at vælge at indarbejde opmærksomme, sund livsstil valg og forebyggende sundhedsydelser modaliteter i vores liv i dag, kan vi nyde skyggen i årene fremover.
Anugraha Reiki is one of the many forms of the popular Reiki system of healing. Anugraha Reiki er en af de mange former for populære Reiki system for helbredelse. Reiki has its origins traced back to Japan where the practice was developed by a Tendai Budhhist named Mikao Usui in 1922. Reiki har sin oprindelse spores tilbage til Japan, hvor praksis blev udviklet af en Tendai Budhhist navngivne Mikao Usui i 1922. He was said to have discovered the technique after a 21-day retreat on Mount Kurama. Han var siges at have opdaget teknikken efter en 21-dages retræte på Mount Kurama.
Everyone deserves to be happy. Alle fortjener at være lykkelig. In fact, this can only happen when there is abundance and prosperity which happen to be the basic principles of Reiki. I realiteten kan dette kun ske, når der er overflod og velstand, som tilfældigvis er de grundlæggende principper om Reiki. Abundance and prosperity Reiki can only be achieved by following the five principles namely give cheerfully, change your voice if you want to desire, know your life’s purpose, be aware that there must be no mistakes or regrets and living the mantra. Overflod og velstand Reiki kan kun opnås ved at følge de fem principper, dvs give muntert, ændre din stemme hvis du ønsker at ønske, ved dit liv's formål, være klar over, at der skal være nogen fejl eller beklager og lever det mantra.
Reiki is another form of alternative medicine. Reiki er en anden form for alternativ medicin. Although it can cure certain illnesses, one that has never been thoroughly studied in humans is anemia. Selv om det kan kurere visse sygdomme, som aldrig er blevet grundigt undersøgt hos mennesker er anæmi. Anemia is a common blood disorder and this happens when the person’s red blood cells are below normal. Anæmi er en fælles blodsygdom, og dette sker, når personens røde blodlegemer er mindre end normalt. This often leads to other health problems like fatigue and stress that affects the body’s other organs. Dette fører ofte til andre helbredsproblemer som træthed og stress, der påvirker kroppens andre organer.
Looking for neti pot salt. Leder du efter neti pot salt. Here's a handy guide for you to help you understand what kinds of neti pot salt is available and how to determine which one is right for you. Her er en praktisk guide for dig og hjælpe dig med at forstå, hvilke former for neti pot salt er til rådighed, og hvordan du kan afgøre, hvilken en der er rigtigt for dig. Neti Pot salt is available commercially as prepackaged individual mixes and also it can be found in bulk form. Neti Pot salt findes i handelen som færdigpakkede individuelle blandinger og også det kan findes i løs form. The bulk neti pot salt is usually found in containers or even plastic bags. Hovedparten neti pot salt er normalt findes i containere eller plastposer. Neti salt comes in a variety of strengths or saline concentrations. Neti salt kommer i forskellige styrker og saltholdigt koncentrationer.
Article Directory Home Artikel Directory Home Alternative Medicine Alternativ medicin

Can't find what you're looking for? Kan du ikke finde det, du leder efter? Try Google Search! Prøv Google Search!
(Search in 26 languages: English, Spanish, French, Japanese, Arabic, Italian, German, (Søg på 26 sprog: Engelsk, spansk, fransk, japansk, arabisk, italiensk, tysk,
Chinese Simplified, Chinese Traditional, Dutch, Korean, Portuguese, Russian, Greek, Serbian Chinese Simplified, Traditionelt kinesisk, hollandsk, koreansk, portugisisk, russisk, græsk, serbisk
Slovak, Hebrew, Swedish, Romanian, Polish, Norwegian, Finnish, Danish, Czech, Croatian, Bulgarian) Slovak, hebraisk, svensk, tysk, rumænsk, polsk, norsk, finsk, dansk, tjekkisk, kroatisk, bulgarsk)
(We serve worldwide - Locations updated as at Friday, 05 December 2008 11:57 pm , Singapore) (Vi tjener på verdensplan - Locations opdateret som på fredag den 05 december 2008 11:57, Singapore)
United States of America, USA . United States of America, USA. United Kingdom, UK (England, Scotland, Wales, Northern Ireland) . Forenede Kongerige, UK (England, Skotland, Wales, Nordirland). Canada . Canada. Afghanistan . Albania . Afghanistan. Albanien. Algeria . Algeriet. American Samoa . Amerikansk Samoa. Andorra . Andorra. Angola . Angola. Anguilla . Anguilla. Antarctica . Antarktis. Antigua & Barbuda . Antigua & Barbuda. Argentina . Armenia . Argentina. Armenien. Aruba . Aruba. Australia . Australien. Austria . Østrig. Azerbaijan . Aserbajdsjan. Bahamas . Bahamas. Bahrain . Bahrain. Bangladesh . Bangladesh. Barbados . Barbados. Belarus . Belgium . Belarus. Belgien. Belize . Belize. Benin . Benin. Bermuda . Bermuda. Bhutan . Bhutan. Bolivia . Bolivia. Bonaire . Bonaire. Bosnia-Herzegovina . Bosnien-Hercegovina. Botswana . Botswana. Brazil . Brasilien. British Virgin Islands . Britiske Jomfruøer. Brunei Darrusalam . Brunei Darrusalam. Bulgaria . Bulgarien. Burkina Faso . Burkina Faso. Burundi . Burundi. Cambodia . Cambodja. Cameroon . Cameroun. Cape Verde . Kap Verde. Cayman Islands . Cayman Islands. Central African Republic . Centralafrikanske Republik. Chad . Tchad. Channel Islands . Kanaløerne. Chile . Chile. China . Porcelæn. Christmas Island . Christmas Island. Colombia . Colombia. Comoros . Congo . Comorerne. Congo. Congo (Dem. Rep.) . Congo (Dem. Rep). Cook Islands . Cook Islands. Costa Rica . Costa Rica. Côte d'Ivoire . Côte d'Ivoire. Croatia . Kroatien. Cuba . Cuba. Curacao . Curacao. Cyprus . Cypern. Czech Republic . Tjekkiske Republik. Denmark . Danmark. Djibouti . Djibouti. Dominica . Dominica. Dominican Republic . Dominikanske Republik. East Timor . Østtimor. Ecuador . Ecuador. Egypt . Egypten. El Salvador . Equatorial Guinea . El Salvador. Ækvatorialguinea. Eritrea . Eritrea. Estonia . Estland. Ethiopia . Etiopien. Falkland Islands and Dependencies . Falklandsøerne og afhængigheder. Faroe Islands . Færøerne. Fiji . Fiji. Finland . France . Finland. Frankrig. French Guiana . Fransk Guyana. French Polynesia . Fransk Polynesien. Gabon . Gabon. Gambia . Gambia. Gaza . Gaza. Georgia . Georgien. Germany . Tyskland. Ghana . Ghana. Gibraltar . Gibraltar. Greece . Greenland . Grækenland. Grønland. Grenada . Grenada. Guadeloupe . Guadeloupe. Guam . Guam. Guatemala . Guatemala. Guinea . Guinea. Guinea-Bissau . Guinea-Bissau. Guyana . Guyana. Haiti . Haiti. Hawaiian Islands . Honduras . Hawaii-øerne. Honduras. Hong Kong . Hong Kong. Hungary . Ungarn. Iceland . Island. India . Indien. Indonesia . Indonesien. Iran . Iran. Iraq . Irak. Isle Of Man . Isle of Man. Israel . Israel. Italy . Ivory Coast . Italien. Elfenbenskysten. Jamaica . Jamaica. Japan . Japan. Johnston Atoll . Johnston Atoll. Jordan . Jordan. Kazakhstan . Kasakhstan. Kenya . Kenya. Kiribati . Kiribati. Korea (North) . Korea (South) . Korea (Nord). Korea (Syd). Kuwait . Kuwait. Kyrgyzstan . Kirgisistan. Laos . Laos. Latvia . Letland. Lebanon . Libanon. Leeward Islands . Leeward Islands. Lesotho . Lesotho. Liberia . Liberia. Libya . Liechtenstein . Libyen. Liechtenstein. Lithuania . Litauen. Luxembourg . Luxembourg. Macau . Macau. Macedonia . Makedonien. Madagascar . Madagaskar. Malawi . Malawi. Malaysia . Malaysia. Maldives . Maldiverne. Mali . Malta . Mali. Malta. Marshall Islands . Marshall-øerne. Martinique . Martinique. Mauritania . Mauretanien. Mauritius . Mauritius. Mexico . Mexico. Micronesia (Federated States) . Mikronesien (Federated States). Midway Islands . Midway-øerne. Moldova . Moldova. Monaco . Monaco. Mongolia . Mongoliet. Montserrat . Montserrat. Morocco . Marokko. Mosquito Coast . Myg Coast. Mozambique . Mozambique. Myanmar (Burma) . Namibia . Myanmar (Burma). Namibia. Nauru . Nauru. Navassa Island . Navassa Island. Nepal . Nepal. Netherlands . Nederlandene. Netherlands Antilles . Nederlandske Antiller. New Caledonia . Ny Kaledonien. New Zealand . Nicaragua . New Zealand. Nicaragua. Niger . Niger. Nigeria . Nigeria. Niue . Niue. Norfolk Island . Norfolk Island. Northern Mariana Islands . Nordmarianerne. Norway . Norge. Oman . Oman. Pakistan . Pakistan. Palau . Palestine . Palau. Palæstina. Panama . Panama. Papua New Guinea . Papua Ny Guinea. Paracel Islands . Paracel Islands. Paraguay . Paraguay. Peru . Peru. Philippines . Filippinerne. Pitcairn Islands . Pitcairn Islands. Poland . Portugal . Polen. Portugal. Puerto Rico . Puerto Rico. Qatar . Qatar. Reunion . Reunion. Romania . Rumænien. Russia . Rusland. Rwanda . Rwanda. Ryukyu Islands . Ryukyu Øer. Saint Helena . Saint Helena. Saint Kitts and Nevis . Saint Kitts og Nevis. Saint Lucia . Saint Lucia. Saint Pierre & Miquelon . Saint Pierre og Miquelon. Saint Vincent & The Grenadines . Saint Vincent & Grenadinerne. Samoa . Samoa. San Marino . San Marino. São Tom?& Príncipe . Sao Tom? & Príncipe. Saudi Arabia . Saudi-Arabien. Senegal . Senegal. Serbia . Serbien. Seychelles . Seychellerne. Sierra Leone . Sierra Leone. Singapore . Singapore. Slovakia . Slovakiet. Slovenia . Slovenien. Solomon Islands . Salomonøerne. Somalia . Somalia. South Africa . Sydafrika. Spain . Spanien. Sri Lanka . Sri Lanka. Sudan . Sudan. Suriname . Surinam. Swaziland . Swaziland. Sweden . Sverige. Switzerland . Schweiz. Syria . Taiwan . Syrien. Taiwan. Tajikistan . Tadsjikistan. Tanzania . Tanzania. Thailand . Thailand. Togo . Togo. Tonga . Tonga. Transkei . Transkei. Trinidad & Tobago . Trinidad & Tobago. Tunisia . Tunesien. Turkey . Turkmenistan . Tyrkiet. Turkmenistan. Turks and Caicos Islands . Turks-og Caicosøerne. Tuvalu . Tuvalu. US Virgin Islands . US Virgin Islands. Uganda . Uganda. Ukraine . Ukraine. United Arab Emirates . Upper Volta . Forenede Arabiske Emirater. Øvre Volta. Uruguay . Uruguay. Uzbekistan . Usbekistan. Vanuatu . Vanuatu. Vatican City (Holy See) . Vatikanstaten (Pavestolen). Venezuela . Venezuela. Vietnam . Vietnam. Wake Island . Windward Islands . Wake Island. Windward Islands. Yemen . Yemen. Yugoslavia . Jugoslavien. Zaire . Zaire. Zambia . Zambia. Zimbabwe
Copyright © 2005 - Copyright © 2005 -- by Larry Lim , Singapore - Article Search Engine Directory at ArticleSphere.com™ af Larry Lim, Singapore - Artikel Search Engine Directory på ArticleSphere.com ™
All Rights Reserved Worldwide. All rights reserved Worldwide. All Trademarks and Servicemarks are the property of the respective owners. Alle varemærker og tjenestemærker tilhører de respektive ejere.
Template Design by Internet Marketing Singapore | Internet Marketing | Singapore Classified Skabelon designet af Internet Marketing Singapore | Internet Marketing | Singapore klassificeret
English